ECG AI Algorithm txheeb xyuas sab laug ventricular Systolic Dysfunction
Tso lus
ECG AI algorithm txheeb xyuas sab laug ventricular systolic tsis ua haujlwm
Cov neeg mob tuaj rau hauv chav kho mob xwm txheej ceev (ED) nrog dyspnea tau sab laug ventricular (LV) systolic dysfunction, siv electrocardiograms soj ntsuam los ntawm AI.
Demilade Adedinsewo, MD, tus kws tshawb fawb tseem ceeb hauv Department of Cardiovascular Medicine ntawm Mayo Clinic hauv Jacksonville, Florida, hais rau Healio: "AI ECG tuaj yeem kuaj xyuas sab laug ventricular systolic ua haujlwm sai dua thiab raug rau cov neeg mob uas ua tsis taus pa ntau dua NT-proBNP. Txhim kho thiab ua kom sai sai lub chaw kuaj mob xwm txheej ceev thiab muab lub sijhawm tshwj xeeb los txheeb xyuas cov neeg mob plawv uas muaj kev pheej hmoo siab ua ntej thiab txuas cov neeg mob mus rau kev kho mob plawv. "
cov neeg mob ua tsis taus pa
Hauv kev tshawb nrhiav rov qab, luam tawm hauv Circulation: Arrhythmias thiab Electrophysiology, cov kws tshawb fawb tau tshuaj xyuas cov ntaub ntawv los ntawm 1,606 tus neeg mob (hnub nyoog nruab nrab 68; 47 feem pua cov poj niam) thaum lub Tsib Hlis 2018 thiab 2019 Ua pa nyuaj rau 2 lub hlis. Cov neeg mob no muaj tsawg kawg ib ECG hauv 24 teev thiab hauv 30 hnub ntawm lawv mus ntsib ED. Cov neeg uas tau kuaj pom yav dhau los systolic, diastolic, lossis tsis tau piav qhia lub plawv tsis ua haujlwm raug cais tawm.
Cov txiaj ntsig tseem ceeb ntawm txoj kev tshawb fawb no yog kev txheeb xyuas cov neeg mob tshiab nrog LV systolic dysfunction (txhais tias yog ib feem ntawm sab laug ventricular ejection feem ntawm 35 feem pua lossis tsawg dua) hauv 30 hnub ntawm ED mus ntsib. Cov txiaj ntsig thib ob tau txhais tias yog cov neeg mob uas muaj cov kab mob sab laug ventricular ejection feem (LVEF) tsawg dua 50 feem pua hauv 30 hnub ntawm kev nthuav qhia. Ob qhov txiaj ntsig tau txiav txim siab los ntawm ECGs soj ntsuam los ntawm kev kawm sib sib zog nqus, AI-ECG algorithm tsim thiab siv tau los txheeb xyuas LVEFs ntawm 35 feem pua lossis qis dua yam tsis muaj kev txhim kho ntxiv lossis kev cob qhia.
Lub sijhawm nruab nrab ntawm ECG tom qab ED mus ntsib yog 1 hnub.
Hauv cov neeg mob thaum muaj xwm txheej ceev nrog kev ua tsis taus pa, thaj chaw nyob hauv qab tus neeg txais kev ua haujlwm tus yam ntxwv nkhaus rau AI-ECG algorithm txhawm rau txheeb xyuas cov kab mob ventricular systolic tshiab yog 0.89 (95 feem pua CI, 0.{{5} }.91). Lub algorithm muaj qhov tseeb ntawm 85.9 feem pua (95 feem pua CI, 84.1-87.6), qhov tseeb ntawm 87 feem pua, rhiab heev ntawm 74 feem pua, qhov zoo kwv yees tus nqi ntawm 40 feem pua, thiab tus nqi kwv yees tsis zoo ntawm 97 feem pua.
Lub algorithm kuj tseem tuaj yeem txheeb xyuas cov neeg mob uas muaj LVEF qis dua 50 feem pua nrog thaj chaw hauv qab tus neeg txais kev ua haujlwm ntawm tus yam ntxwv nkhaus ntawm 0.85 (95 feem pua CI, 0.83-0.88 ) nrog qhov tseeb ntawm 86 feem pua (95 feem pua CI, 84.{10}}.7). Qhov no kuj tau ua tiav qhov tshwj xeeb ntawm 91 feem pua, rhiab heev ntawm 63 feem pua, tus nqi kwv yees zoo ntawm 62 feem pua, thiab tus nqi kwv yees tsis zoo ntawm 92 feem pua.
Cov kws tshawb fawb kuj tau soj ntsuam lub vaj huam sib luag ntawm {{0}} cov neeg mob uas muaj N-terminal B-hom natriuretic peptide qhov tseem ceeb. NT-proBNP qib siab dua 800 pg/mL qhia LV systolic dysfunction tshiab, nrog thaj tsam hauv qab tus neeg txais kev ua haujlwm ntawm tus yam ntxwv nkhaus ntawm 0.8 (95 feem pua CI, 0.76-0.84).
"Txoj kev tshawb fawb tam sim no yog rov qab los, thiab cov kev tshawb fawb yav tom ntej yog xav tau los ntsuas qhov cuam tshuam ntawm AI-ECG ntawm cov txiaj ntsig kev kho mob mus ntev, uas peb pab neeg tshawb fawb tam sim no ntsuas," Adedinsewo tau hais hauv kev xam phaj.
Adedinsewo ntxiv tias cov cuab yeej siv tam sim no tau siv thoob plaws hauv nws txoj kev noj qab haus huv. Nws hais rau Healio: "Lub cuab yeej AI-ECG tam sim no muaj nyob rau ntawm txhua qhov chaw Mayo Clinic thiab nkag mus tau los ntawm peb cov ntaub ntawv kho mob hluav taws xob, ntxiv rau, cov cuab yeej tam sim no tau tso cai siv thaum muaj xwm txheej ceev los ntawm FDA hauv lub Tsib Hlis rau kev tshuaj ntsuam xyuas kev kuaj mob lossis sab laug. ventricular dysfunction nyob rau hauv cov neeg mob uas xav tias tus tshiab coronavirus. "
Lub peev xwm los txhawb kev saib xyuas neeg mob
Nyob rau hauv ib tsab xov xwm hais txog, Dr. Kazi T. Haq ntawm Knight Cardiovascular Institute ntawm Oregon Health thiab Science University hauv Portland, Oregon, thiab cov npoj yaig tau sau tias: "Zuag qhia tag nrho, qhov kev tshawb pom ntawm Adedinsewo li al. qhia tias— AI siv tus qauv {{ 0}}lead ECG cov hlau lead-wire ECG tuaj yeem txhim kho qhov kev txheeb xyuas ntawm lub plawv tsis ua haujlwm tshiab hauv cov neeg mob thaum muaj xwm txheej ceev.
